常鑫，博士，校聘副教授
地址：武汉市东湖新技术开发区光谷一路206号，yh533388银河最新地址
邮编：430205
邮箱：xinchangemail@163.com
教育背景
2015/09-2020.06，武汉大学，有机化学，博士
2011/09-2015/06，信阳师范大学，化学，学士
工作履历
2025/09-至今，武汉工程大学，校聘副教授
2023/11-2025/07，Boston College，博士后
2020/07-2023/05，武汉大学，博士后
科研项目
1. 国家自然科学基金青年项目，22101216，30万，主持
2. 中国博士后科学基金面上项目，2021M702514，8万，主持
3. 武汉工程大学科学基金，10万，主持
研究领域
1. 金属催化的不对称合成；
2. 新型有机光电化学反应研究；
3. 药物合成及绿色工艺的开发
代表性论文：
1. Chang, X.;# Yang, Y.;# Shen, C.; Xue, K.-S.; Wang, Z.-F.; Cong, H.; Tao, H.-Y.; Chung, L. W.*; Wang, C.-J.* β-Substituted Alkenyl Heteroarenes as Dipolarophiles in the Cu(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides Empowered by a Dual Activation Strategy: Stereoselectivity and Mechanistic Insight. J. Am. Chem. Soc. 2021, 143, 3519-3535. (#共同第一作者, 一区top)
2. Chang, X.; Cheng, X.; Liu, X.-T.; Fu, C.; Wang, W.-Y.; Wang, C.-J.* Stereodivergent Construction of 1,4-Nonadjacent Stereocenters via Hydroalkylation of Racemic Allylic Alcohols Enabled by Copper/Ruthenium Relay Catalysis. Angew. Chem. Int. Ed. 2022, 61, e202206517. (VIP, 一区top)
3. Xiao, L.;# Chang, X.;# Xu, H.;# Xiong, Q; Dang, Y.*; Wang, C.-J.* Stereodivergent Construction of 1,4-Nonadjacent Stereocenters via Hydroalkylation of Racemic Allylic Alcohols Enabled by Copper/Ruthenium Relay Catalysis. Angew. Chem. Int. Ed. 2022, 61, e202212948. (#共同第一作者, 一区top)
4. Cheng, X.;# Chang, X.;# Yang, Y.;# Zhang, Z.; Li, J.; Li, Y; Zhao, W.; Chung, L. W.*; Teng H.*; Dong, X.-Q.*; Wang, C.-J.* Copper-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with β-trifluoromethyl substituted alkenyl heteroarenes. Sci. China Chem., 2023, 66, 3193-3204. (#共同第一作者, 一区top)
5. Chang, X.; Che, C.; Wang, Z.-F.; Wang, C.-J.* Palladium-Catalyzed Asymmetric Allylic Alkylation/α-Iminol Rearrangement: A Facile Access to 2-Spirocyclic-Indoline Derivatives. CCS Chem. 2022, 4, 1414-1428. (一区top)
6. Chang, X.;# Liu, X.-T.;# Li, F.;# Yang, Y.; Chung, L. W.*; Wang, C.-J.* Electron-rich benzofulvenes as effective dipolarophiles in copper(i)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides. Chem. Sci. 2023, 14, 5460-5469. (#共同第一作者, 一区top)
7. Chang, X.;# Cheng, X.;# Wang, C.-J.* Catalytic asymmetric synthesis of enantioenriched α-deuterated pyrrolidine derivatives. Chem. Sci. 2022, 13, 4041-4049. (#共同第一作者, 一区top)
8. Chang, X.;# Ran, J.-D.;# Liu, X.-T.; Wang, C.-J.* Catalytic Asymmetric Benzylation of Azomethine Ylides Enabled by Synergistic Lewis Acid/Palladium Catalysis. Org. Lett. 2022 24, 2573-2578. (#共同第一作者)
9. Fu, C.;# Chang, X.;# Xiao, L.; Wang, C. J.* Stereodivergent Synthesis of Enantioenriched α-Deuterated α-Amino Acids via Cascade Cu(I)-Catalyzed H–D Exchange and Dual Cu- and Ir-Catalyzed Allylation. Org. Lett. 2022, 24, 5562-5567. (#共同第一作者)
10. Sun, X.-S.#; Chang, X.#; Shi, L.-M.#; Wang, Z.-F.; Wei, L.; Wang, C.-J.* Palladium catalyzed cascade umpolung allylation/acetalation for the construction of quaternary 3-amino oxindoles. Chem. Commun. 2021, 57, 7958-7961. (#共同第一作者)
11. Chang, X.; Sun, X.-S.; Che, C.; Hu, Y.-Z.; Tao, H.-Y.; Wang, C.-J.* Copper(I)-Catalyzed Kinetic Resolution of exo-3-Oxodicyclopentadienes and endo-3-Oxodicyclopentadiene. Org. Lett. 2019, 21, 1191-1196.
12. Liu, K.#; Chang, X.#; Wang, C.-J.* Nickel(II)-Catalyzed Cascade Vinylogous Mukaiyama 1,6-Michael/Michael Addition of 2-Silyloxyfuran with N-Sulfonyl-1-aza-1,3-dienes: Access to Fused Piperidine/Butyrolactone Skeletons. Org. Lett. 2016, 18, 6288-6291. (#共同第一作者).
